Determination of diclofenac residue in swine tissue following intramuscular administration
نویسندگان
چکیده
منابع مشابه
Residue depletion of colistin in swine after intramuscular administration.
A newly formulated colistin sulphate solution was prepared in a previous study as a potential agent for intramuscular injection and its effectiveness, toxicity and pharmacokinetics were investigated. In order to provide more information to establish scientific guidance for safe use of this preparation, its residue depletion in swine tissues following intramuscular administration was investigate...
متن کاملPharmacokinetics of diclofenac in sheep following intravenous and intramuscular administration.
OBJECTIVES The aim of this work was to examine the pharmacokinetics of diclofenac (DCLF) in sheep after intravenous (IV) and intramuscular (IM) dosing. ANIMALS Healthy male Najdi sheep. MATERIALS AND METHODS Diclofenac (1 mg kg(-1)) was administered to ten clinically healthy-male Najdi sheep IV or IM (n = 5 each). Blood samples (5 mL) were collected and serum was separated for drug analysis...
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Nicolau syndrome (livedoid dermatitis) is a rare adverse reaction of a still largely unidentified pathogenesis at the site of intramuscular drug injection. The typical presentation is pain around the injection site soon after injection, followed by erythema, livedoid patch, haemorrhagic patch, and finally necrosis of skin, subcutaneous fat, and muscle tissue. The phenomenon has been related to ...
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In circumstances such as in vitro fertilization (IVF) or in patients with luteal phase defect, one needs to ensure the establishment of pregnancy as soon as possible. At the same time, a question arises: How can a physician make sure that the β-hCG is of an endogenous source and not the residue of the prescribed drugs (hCG)? In this article we have studied the elimination time of 1M inject...
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ژورنال
عنوان ژورنال: Veterinarski glasnik
سال: 2005
ISSN: 0350-2457,2406-0771
DOI: 10.2298/vetgl0506603p